Clinical significance of BRAF/NRAS concurrent mutations in a clinic-based metastatic melanoma cohort

L Del Regno; B Louveau; M Battistella; A Sadoux; B Baroudjian; J Delyon; K Serror; C Allayous; C Lebbe; S Mourah; F Jouenne

doi:10.1111/bjd.18641

Clinical significance of BRAF/NRAS concurrent mutations in a clinic-based metastatic melanoma cohort

Br J Dermatol. 2020 May;182(5):1281-1283. doi: 10.1111/bjd.18641. Epub 2019 Dec 2.

Authors

L Del Regno¹, B Louveau^{2

3

4}, M Battistella^{2

3

5}, A Sadoux⁴, B Baroudjian^{2

6}, J Delyon^{2

3

6}, K Serror⁷, C Allayous^{2

6}, C Lebbe^{2

3

6}, S Mourah^{2

3

4}, F Jouenne^{2

3

4}

Affiliations

¹ Institute of Dermatology, Catholic University - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
² INSERM, UMR_S976, Paris, France.
³ Université de Paris, Paris, France.
⁴ Department of Pharmacogenomics, Hôpital Saint-Louis, Assistance Publique - Hôpitaux de Paris, 1 Avenue Claude Vellefaux, 75475, Paris cedex 10, France.
⁵ Department of Pathology, Hôpital Saint-Louis, Assistance Publique - Hôpitaux de Paris, 1 Avenue Claude Vellefaux, 75475, Paris cedex 10, France.
⁶ Department of Dermatology, Hôpital Saint-Louis, Assistance Publique - Hôpitaux de Paris, 1 Avenue Claude Vellefaux, 75475, Paris cedex 10, France.
⁷ General Surgery, Hôpital Saint-Louis, Assistance Publique - Hôpitaux de Paris, 1 Avenue Claude Vellefaux, 75475, Paris cedex 10, France.

PMID: 31675434
DOI: 10.1111/bjd.18641

No abstract available

Publication types

Letter

MeSH terms

Cohort Studies
DNA Mutational Analysis
GTP Phosphohydrolases / genetics
Humans
Melanoma* / genetics
Membrane Proteins / genetics
Mutation / genetics
Proto-Oncogene Proteins B-raf / genetics
Skin Neoplasms* / genetics

Substances

Membrane Proteins
BRAF protein, human
Proto-Oncogene Proteins B-raf
GTP Phosphohydrolases
NRAS protein, human