Erbium: Yttrium Aluminum Garnet Laser Accelerates Healing in Indolent Diabetic Foot Ulcers

J Foot Ankle Surg. 2019 Nov;58(6):1077-1080. doi: 10.1053/j.jfas.2019.07.023.

Abstract

The objective of the study was to evaluate the effect of the erbium:yttrium aluminum garnet (YAG) laser on diabetic foot ulcers (DFUs) that had not responded to standard care. We retrospectively evaluated 22 nonhealing DFUs that received at least 4 weeks of standard wound care, demonstrated poor healing response, and subsequently were treated with an erbium:YAG laser. We measured the percent wound area reduction (PWAR) for the 4 weeks before initiating laser therapy and the PWAR for 4 weeks after the initiation of laser therapy. Erbium:YAG laser treatment consisted of 2 components: debridement and resurfacing. The laser settings were the same for all treatments. We used the paired t test to compare pretreatment with posttreatment wound area reduction. During the 4-week period before the initiation of laser therapy, the average PWAR was -33.6%. Four weeks after initiating treatment with the erbium:YAG laser, the average PWAR was 63.4% (p = .002) and 72.7% of wounds had ≥50% PWAR. By 12 weeks, 50% of wounds had healed. Erbium:YAG laser therapy accelerated DFU healing in a cohort of patients with ulcers that had been unresponsive to standard of care therapy.

Keywords: debridement; healing; laser; percent wound area reduction; treatment.

MeSH terms

  • Aluminum
  • Diabetic Foot / radiotherapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Lasers, Solid-State / therapeutic use*
  • Low-Level Light Therapy / methods*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome
  • Wound Healing / radiation effects*
  • Yttrium

Substances

  • yttrium-aluminum-garnet
  • Yttrium
  • Aluminum