Assembly and Analysis of the Genome Sequence of the Yeast Brettanomyces naardenensis CBS 7540

Ievgeniia A Tiukova; Huifeng Jiang; Jacques Dainat; Marc P Hoeppner; Henrik Lantz; Jure Piskur; Mats Sandgren; Jens Nielsen; Zhenglong Gu; Volkmar Passoth

doi:10.3390/microorganisms7110489

Assembly and Analysis of the Genome Sequence of the Yeast Brettanomyces naardenensis CBS 7540

Microorganisms. 2019 Oct 26;7(11):489. doi: 10.3390/microorganisms7110489.

Authors

Ievgeniia A Tiukova^{1

2}, Huifeng Jiang³, Jacques Dainat^{4

5}, Marc P Hoeppner^{4

5

6}, Henrik Lantz^{4

5}, Jure Piskur⁷, Mats Sandgren², Jens Nielsen¹, Zhenglong Gu⁸, Volkmar Passoth²

Affiliations

¹ Department of Biology and Biological Engineering, Systems and Synthetic Biology, Chalmers University of Technology, SE-412 96 Göteborg, Sweden.
² Department of Molecular Sciences, Swedish University of Agricultural Sciences, Box 7015, SE-75007 Uppsala, Sweden.
³ Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
⁴ Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 752 37 Uppsala, Sweden.
⁵ National Bioinformatics Infrastructure Sweden (NBIS), 752 37 Uppsala, Sweden.
⁶ Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, 24118 Kiel, Germany.
⁷ Department of Biology, Lund University, 223 62 Lund, Sweden.
⁸ Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.

Abstract

Brettanomyces naardenensis is a spoilage yeast with potential for biotechnological applications for production of innovative beverages with low alcohol content and high attenuation degree. Here, we present the first annotated genome of B. naardenensis CBS 7540. The genome of B. naardenensis CBS 7540 was assembled into 76 contigs, totaling 11,283,072 nucleotides. In total, 5168 protein-coding sequences were annotated. The study provides functional genome annotation, phylogenetic analysis, and discusses genetic determinants behind notable stress tolerance and biotechnological potential of B. naardenensis.

Keywords: Brettanomyces naardenensis; genome; yeast.

Abstract

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