Meningeal and multiorgan disseminated sporotrichosis: A case report and autopsy study

Helena Duani; Marina Fernandes Palmerston; Jésus Faria Rosa Júnior; Vitor Teatini Ribeiro; Pedro Lobo Alcântara Neves

doi:10.1016/j.mmcr.2019.10.005

Meningeal and multiorgan disseminated sporotrichosis: A case report and autopsy study

Med Mycol Case Rep. 2019 Oct 31:26:47-52. doi: 10.1016/j.mmcr.2019.10.005. eCollection 2019 Dec.

Authors

Helena Duani¹, Marina Fernandes Palmerston¹, Jésus Faria Rosa Júnior², Vitor Teatini Ribeiro¹, Pedro Lobo Alcântara Neves²

Affiliations

¹ Tropical Medicine and Infectious Diseases Section, Hospital das Clínicas, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
² Department of Pathologic Anatomy and Legal Medicine, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Abstract

This case report presents a 36-year old man with a disseminated sporotrichosis who presented with seizures and crusted lesions all over the body. Imaging studies revealed acute ischemic brain event with haemorrhagic transformation in right frontal lobe. Skin biopsy showed Sporothrix schenckii. He was treated with standard amphotericin B. Despite therapy, he developed consciousness loss, multiorgan-failure and eventually expired. Necropsy findings showed renal, hepatic, splenic, prostate, testicles and meningeal/cerebral involvement.

Keywords: Brazil; Endemic mycoses; Necropsy; Sporothrix brasiliensis; Sporothrix schenckii; Sporotrichosis.

Publication types

Case Reports