Evolution of Highly Pathogenic Avian Influenza A(H5N1) Virus in Poultry, Togo, 2018

Emerg Infect Dis. 2019 Dec;25(12):2287-2289. doi: 10.3201/eid2512.190054.

Abstract

In 2015, highly pathogenic avian influenza A(H5N1) viruses reemerged in poultry in West Africa. We describe the introduction of a reassortant clade 2.3.2.1c virus into Togo in April 2018. Our findings signal further local spread and evolution of these viruses, which could affect animal and human health.

Keywords: Africa; Côte d’Ivoire; H5N1; Togo; genetic evolution; highly pathogenic avian influenza; influenza virus; molecular clock; phylogeny; poultry; reassortment; respiratory infections; viruses; zoonoses.

Publication types

  • Historical Article
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Biological Evolution*
  • Hemagglutinin Glycoproteins, Influenza Virus / genetics
  • History, 21st Century
  • Influenza A Virus, H5N1 Subtype / classification*
  • Influenza A Virus, H5N1 Subtype / genetics*
  • Influenza in Birds / epidemiology*
  • Influenza in Birds / history
  • Influenza in Birds / virology*
  • Neuraminidase / genetics
  • Poultry / virology*
  • Public Health Surveillance
  • Togo / epidemiology
  • Viral Proteins / genetics

Substances

  • Hemagglutinin Glycoproteins, Influenza Virus
  • Viral Proteins
  • NA protein, influenza A virus
  • Neuraminidase