A magnetic resonance imaging (MRI) study of 12 chronic schizophrenic outpatients (4 females and 8 males) and 12 healthy volunteers, individually matched for age and sex, found a significantly larger ventricle-brain ratio and smaller corpus callosum area in schizophrenics than in controls. There were no statistically significant differences in the image intensity values between schizophrenic and healthy volunteer groups. However, there were more intragroup differences (left-right) of the image intensity values in the SE-30 sequence than in the SE-120 sequence in schizophrenics than in normals.