[EB virus-positive follicular lymphoma in lymph node: report of a case]

Zhonghua Bing Li Xue Za Zhi. 2019 Nov 8;48(11):895-897. doi: 10.3760/cma.j.issn.0529-5807.2019.11.014.
[Article in Chinese]

Abstract

EB病毒阳性滤泡性淋巴瘤(follicular lymphoma, FL)是一种罕见的B细胞淋巴瘤,在同一级别的FL中,EB病毒阳性与EB病毒阴性的FL,在形态学和免疫表型上难以区分,EB病毒编码的小RNA(EBER)检测尤为重要。且大多数EB病毒阳性FL的患者更易进展为更高级别的FL或弥漫性大B细胞淋巴瘤。该文报道1例淋巴结EB病毒阳性FL。镜下形态、免疫组织化学染色及荧光原位杂交检测均符合FL,特殊之处在于EBER只表达于肿瘤性滤泡内的细胞。最终诊断为淋巴结EB病毒阳性的FL。.

Publication types

  • Case Reports

MeSH terms

  • Herpesvirus 4, Human
  • Humans
  • Lymph Nodes
  • Lymphoma, Follicular*