Label-Free Detection of Transferrin Receptor by a Designed Ligand-Protein Sensor

Chem Asian J. 2020 Jan 2;15(1):56-60. doi: 10.1002/asia.201901512. Epub 2019 Nov 28.

Abstract

Advanced detection of biomarkers in biofluids plays an important role in disease diagnosis and prognosis. Current techniques with pre-labelling suffer from high cost and complicated operation, etc. Herein, we designed a label-free electrochemical biosensor for rapid detection of transferrin receptor with desirable linear range, sensitivity, specificity, reproducibility, and stability for practical applications.

Keywords: biomarker; electrochemistry; interface; label-free; sensor.

MeSH terms

  • Biosensing Techniques*
  • Electrochemical Techniques*
  • Ligands
  • Nanotubes, Carbon / chemistry*
  • Receptors, Transferrin / blood*

Substances

  • Ligands
  • Nanotubes, Carbon
  • Receptors, Transferrin