Comparison of dynamic brain metabolism during antegrade cerebral perfusion versus deep hypothermic circulatory arrest using proton magnetic resonance spectroscopy

J Thorac Cardiovasc Surg. 2020 Oct;160(4):e225-e227. doi: 10.1016/j.jtcvs.2019.10.103. Epub 2019 Nov 5.

Abstract

Brain metabolism during deep hypothermic arrest is active and abnormal, resulting in a buildup of lactate and loss of energy substrates. Antegrade cerebral perfusion prevents these abnormalities.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / diagnostic imaging
  • Brain / metabolism*
  • Circulatory Arrest, Deep Hypothermia Induced / methods*
  • Proton Magnetic Resonance Spectroscopy / methods*