Generation of an induced pluripotent stem cell line (SYSUi002-A) from a patient with coronary slow flow phenomenon

Xingqiang Lai; Boxiong Jiang; Jia Liu; Yina Wang; Guifu Wu

doi:10.1016/j.scr.2019.101646

Generation of an induced pluripotent stem cell line (SYSUi002-A) from a patient with coronary slow flow phenomenon

Stem Cell Res. 2019 Dec:41:101646. doi: 10.1016/j.scr.2019.101646. Epub 2019 Nov 2.

Authors

Xingqiang Lai¹, Boxiong Jiang², Jia Liu², Yina Wang³, Guifu Wu⁴

Affiliations

¹ Cardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-sen University, Shennan Middle Road 3025#, Shenzhen 518033, China; Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong, China; Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China.
² VIP Medical Service Center, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou, China.
³ VIP Medical Service Center, The Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Tianhe District, Guangzhou, China. Electronic address: [email protected].
⁴ Cardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-sen University, Shennan Middle Road 3025#, Shenzhen 518033, China. Electronic address: [email protected].

PMID: 31783296
DOI: 10.1016/j.scr.2019.101646

Abstract

The coronary slow flow phenomenon (CSFP) is characterized by delayed progression of the injected contrast medium through the coronary tree during coronary angiography due to unknown mechanisms. Here, a human induced pluripotent stem cell (iPSC) line (SYSUi002-A) was established using the Sendai-virus delivery system from dermal fibroblasts of a CSFP patient. This cell line may represent a valuable tool for investigating the pathogenesis and therapeutic strategies of CSFP.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Culture Techniques / methods*
Cell Line / pathology*
Humans
Induced Pluripotent Stem Cells / pathology*
Male
Middle Aged
No-Reflow Phenomenon / pathology*
Reproducibility of Results