Toxoplasma gondii: How fatal is it in pediatric allogeneic bone marrow transplantation setting?

Transpl Infect Dis. 2020 Feb;22(1):e13226. doi: 10.1111/tid.13226. Epub 2019 Dec 12.

Abstract

Toxoplasmosis is a disease of the immunocompetent population. However, cases of toxoplasma infection associated with immunosuppression have been reported, especially the first months after transplantation. Limited data are available about toxoplasma infection, occurring even many months post-transplant in pediatric patients with nonmalignant and malignant diseases. We report the cases of three patients with early and late disseminated toxoplasmosis and review the literature.

Keywords: Toxoplasmosis; pediatric; transplantation.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Bone Marrow Transplantation / adverse effects*
  • Fatal Outcome
  • Female
  • Humans
  • Immunocompromised Host
  • Male
  • Toxoplasma
  • Toxoplasmosis / blood
  • Toxoplasmosis / diagnostic imaging*