Abstract
A kind of light-responsive vesicle was prepared by aqueous self-assembly of α-CD and an azobenzene-containing M-helical foldamer, which displayed dynamic disassembly-reassembly structural transformation when alternately irradiated by UV and visible light. Distinctively, this vesicle also exhibited enantioselective release abilities toward racemic propranolol (a β-blocker), owing to the M-helical building blocks.
MeSH terms
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Azo Compounds / chemistry
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Azo Compounds / radiation effects
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Drug Carriers / chemistry*
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Drug Carriers / radiation effects
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Drug Liberation / radiation effects
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Liposomes / chemistry*
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Liposomes / radiation effects
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Molecular Conformation
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Propranolol / chemistry
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Quinolines / chemistry
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Quinolines / radiation effects
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Stereoisomerism
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Ultraviolet Rays
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alpha-Cyclodextrins / chemistry*
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alpha-Cyclodextrins / radiation effects
Substances
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Azo Compounds
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Drug Carriers
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Liposomes
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Quinolines
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alpha-Cyclodextrins
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Propranolol