Identification of a novel TFG-FGFR1 fusion gene in an acute myeloid leukaemia patient with t(3;8)(q12;p11)

Tingjing Wang; Zheng Wang; Ling Zhang; Lijun Wen; Wenzhi Cai; Xiaofei Yang; Jinlan Pan; Changgeng Ruan; Depei Wu; Aining Sun; Suning Chen

doi:10.1111/bjh.16294

Identification of a novel TFG-FGFR1 fusion gene in an acute myeloid leukaemia patient with t(3;8)(q12;p11)

Br J Haematol. 2020 Jan;188(1):177-181. doi: 10.1111/bjh.16294. Epub 2019 Dec 4.

Authors

Tingjing Wang¹, Zheng Wang¹, Ling Zhang¹, Lijun Wen¹, Wenzhi Cai¹, Xiaofei Yang¹, Jinlan Pan¹, Changgeng Ruan¹, Depei Wu^{1

2}, Aining Sun¹, Suning Chen^{1

2}

Affiliations

¹ Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, P.R. China.
² Collaborative Innovation Center of Hematology, Institute of Blood and Marrow Transplantation, Soochow University, Suzhou, P.R. China.

PMID: 31802477
DOI: 10.1111/bjh.16294

No abstract available

Keywords: 8p11 myeloproliferative syndrome; TRK-fused gene; acute myeloid leukaemia; fibroblast growth factor receptor 1; tyrosine kinase inhibitors.

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Chromosomes, Human, Pair 3 / genetics*
Chromosomes, Human, Pair 8 / genetics*
Humans
Leukemia, Myeloid, Acute / genetics*
Male
Middle Aged
Oncogene Proteins, Fusion / genetics*
Proteins / genetics*
Receptor, Fibroblast Growth Factor, Type 1 / genetics*
Translocation, Genetic*

Substances

Oncogene Proteins, Fusion
Proteins
TFG protein, human
FGFR1 protein, human
Receptor, Fibroblast Growth Factor, Type 1

Publication types

MeSH terms

Substances

Grants and funding