Acute calcium channel blocker withdrawal-induced cardiac arrest

L E J Peeters; C A den Uil; L Feyz; P M L A van den Bemt; J Daemen; J Versmissen

Acute calcium channel blocker withdrawal-induced cardiac arrest

Neth J Med. 2019 Dec;77(9):341-343.

Authors

L E J Peeters¹, C A den Uil, L Feyz, P M L A van den Bemt, J Daemen, J Versmissen

Affiliation

¹ Departments of Hospital Pharmacy, Erasmus University Medical Centre, Rotterdam, the Netherlands.

PMID: 31814590

Abstract

Acute withdrawal of calcium channel blockers can lead to the so-called calcium channel blocker withdrawal phenomenon, in particular, when high dosages are used. In the case presented, inadequate drug substitution led to this phenomenon which resulted in a serious course of events. Careful monitoring the process of drug substitution with respect to equal therapeutic dosages is therefore a necessity, especially in vulnerable patients.

Publication types

Case Reports

MeSH terms

Angina Pectoris / drug therapy
Calcium Channel Blockers / administration & dosage*
Calcium Channel Blockers / adverse effects*
Coronary Vasospasm / drug therapy
Diagnosis, Differential
Female
Heart Arrest, Induced / methods*
Humans
Middle Aged
Substance Withdrawal Syndrome / drug therapy*
Treatment Outcome
Verapamil / administration & dosage*
Verapamil / adverse effects*

Substances

Calcium Channel Blockers
Verapamil