[Progress in molecular classification of endometrial cancer and its clinical significance]

M Feng; H Bu; W Wang

doi:10.3760/cma.j.issn.0529-5807.2019.12.021

[Progress in molecular classification of endometrial cancer and its clinical significance]

Zhonghua Bing Li Xue Za Zhi. 2019 Dec 8;48(12):997-1000. doi: 10.3760/cma.j.issn.0529-5807.2019.12.021.

[Article in Chinese]

Authors

M Feng¹, H Bu², W Wang³

Affiliations

¹ Department of Pathology, West China Second University Hospital, Sichuan University; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, China; Laboratory of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China.
² Laboratory of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China.
³ Department of Pathology, West China Second University Hospital, Sichuan University; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, China.

PMID: 31818081
DOI: 10.3760/cma.j.issn.0529-5807.2019.12.021

Abstract

子宫内膜癌在组织学及分子水平上是一组异质性显著的恶性肿瘤，不同的病理类型有其独特的组织学表现及不同的生物学行为。随着患者年轻化的趋势和精准医疗的全面推广，传统子宫内膜癌分类方法在指导个体化治疗、疗效预测、预后评估和遗传综合征筛选等方面的局限性逐渐突显，临床上迫切需要更优化的分型以更准确地反映肿瘤的分子生物学行为，为患者的精准诊疗提供理论和实践基础。本文就子宫内膜癌的传统分类及近年来分子分型的研究进展进行综述，期望为临床诊疗策略提供更具实践意义的分型依据。.

MeSH terms

Endometrial Neoplasms*
Female
Humans
Mutation