Simultaneous osteosarcoma and renal cell carcinoma with BRCA1 mutation in a young male adult with prior oligodendroglioma

Pediatr Blood Cancer. 2020 Mar;67(3):e28116. doi: 10.1002/pbc.28116. Epub 2019 Dec 18.

Authors

Aditi Dhir¹, Rong Li², Geling Li², Joy Dean³, Nathaniel H Robin³, Elizabeth Alva¹

Affiliations

¹ Pediatric Hematology Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
² Division of Pathology, Children's of Alabama, Birmingham, Alabama.
³ Clinical Genetics, University of Alabama at Birmingham, Birmingham, Alabama.

PMID: 31850619
DOI: 10.1002/pbc.28116

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adolescent
Adult
BRCA1 Protein / genetics*
Bone Neoplasms / epidemiology
Bone Neoplasms / genetics
Bone Neoplasms / pathology
Carcinoma, Renal Cell / epidemiology
Carcinoma, Renal Cell / genetics
Carcinoma, Renal Cell / pathology*
Combined Modality Therapy
Humans
Incidence
Kidney Neoplasms / epidemiology
Kidney Neoplasms / genetics
Kidney Neoplasms / pathology
Male
Mutation*
Neoplasms, Multiple Primary / epidemiology
Neoplasms, Multiple Primary / genetics
Neoplasms, Multiple Primary / pathology*
Oligodendroglioma / complications*
Oligodendroglioma / therapy
Osteosarcoma / epidemiology
Osteosarcoma / genetics
Osteosarcoma / pathology*
Prognosis

Substances

BRCA1 Protein
BRCA1 protein, human