Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients

Intensive Care Med Exp. 2019 Dec 23;7(1):74. doi: 10.1186/s40635-019-0287-5.

Charles de Roquetaillade^{1

2}, Khalil Kandara^{1

3}, Morgane Gossez^{1

3}, Estelle Peronnet^{1

4}, Céline Monard⁵, Martin Cour⁶, Thomas Rimmelé^{1

5}, Laurent Argaud⁶, Guillaume Monneret^{7

8}, Fabienne Venet^{1

3}

¹ EA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot Hospital, 69437, Lyon, France.
² Current address: INSERM U942 MArkers in Stressed COndiTions (MASCOT), Hôpital Lariboisière, Lyon Cedex, 03, Paris, France.
³ Immunology Laboratory, Hôpital E. Herriot - Hospices Civils de Lyon, 69437, Lyon, France.
⁴ Joint Research Unit HCL-bioMérieux, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003, Lyon, France.
⁵ Anesthesia and Critical Care Medicine Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
⁶ Intensive Care Medicine Department, Hospices Civils de Lyon, Edouard Herriot Hospital, 69437, Lyon, France.
⁷ EA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot Hospital, 69437, Lyon, France. [email protected].
⁸ Immunology Laboratory, Hôpital E. Herriot - Hospices Civils de Lyon, 69437, Lyon, France. [email protected].

No abstract available

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