Cauda equina syndrome in an ovarian malignant-mixed müllerian tumor with leptomeningeal spread

Joshua D Bernstock; Stuart Ostby; Brandon Fox; Houman Sotoudeh; Andrew Janssen; Yun Jee Kang; Jason Chen; Veeranjaneyulu Prattipati; Galal Elsayed; Gustavo Chagoya; Daisuke Yamashita; Gregory K Friedman; Burt Nabors; Warner K Huh; Mina Lobbous

doi:10.1002/ccr3.2472

Cauda equina syndrome in an ovarian malignant-mixed müllerian tumor with leptomeningeal spread

Clin Case Rep. 2019 Oct 22;7(12):2341-2345. doi: 10.1002/ccr3.2472. eCollection 2019 Dec.

Authors

Affiliations

¹ Department of Neurosurgery Brigham and Women's Hospital Harvard University Boston MA USA.
² Division of Gynecologic Oncology University of Alabama at Birmingham Birmingham AL USA.
³ School of Medicine University of Alabama at Birmingham Birmingham AL USA.
⁴ Department of Radiology, Neuroradiology Section University of Alabama at Birmingham Birmingham AL USA.
⁵ Harvard Medical School Boston MA USA.
⁶ Medical Scientist Training Program University of California Los Angeles CA USA.
⁷ Department of Neurosurgery University of Alabama at Birmingham Birmingham AL USA.
⁸ Division of Pediatric Hematology and Oncology Department of Pediatrics University of Alabama at Birmingham Birmingham AL USA.
⁹ Department of Neurology University of Alabama at Birmingham Birmingham AL USA.

Abstract

Leptomeningeal metastasis is extremely rare in patients with ovarian cancer, but should be considered in patients presenting with neurologic deficits such as cauda equine syndrome. Given its poor prognosis and lack of data currently on management, additional studies are needed to optimize treatment regimens and improve outcomes.

Keywords: cauda equina syndrome; leptomeningeal carcinomatosis; metastasis; ovarian carcinosarcoma; ovarian malignant‐mixed müllerian tumor.

Publication types

Case Reports