In vitro evaluation of the hemostatic effect of method involving the combined use of Hydrofit® and Spongel®

Gen Thorac Cardiovasc Surg. 2020 Sep;68(9):932-937. doi: 10.1007/s11748-019-01282-5. Epub 2020 Jan 1.

Abstract

Objective: We developed an effective hemostatic method using Hydrofit® and a hemostatic gelatin sponge (Spongel®). We evaluated the hemostatic effect in comparison to the conventional silicone sheet method.

Methods: A simulated circuit was created using the pump of a Nipro ventricular assist system and a prosthetic graft. A hole was made in the graft by a needle and three hemostatic methods were applied: the silicone sheet method (SS) using Hydrofit® and a silicone sheet, the bread and butter method (BB) using Hydrofit® and a gelatin sponge instead of a silicone sheet, and French toast method (FT) using Hydrofit® and a gelatin sponge over which water was poured before compression. The amount of leakage before and after the application each of the methods was measured according to the compression time.

Results: In the 60 s compression, the amount of leakage after SS, BB, and FT was 0.4 ± 0.8, 0.2 ± 0.6, and 0 ± 0.0 ml, respectively, and FT showed no leakage. In the 30 s compression, the amount of leakage after SS, BB, and FT was 14.2 ± 27.9, 1.0 ± 3.2, and 7.8 ± 22.6 ml, respectively, and did not differ to a statistically significant extent.

Conclusions: The method of combining Hydrofit® and Spongel® could obtain reliable hemostasis in 60 s.

Keywords: Aortic surgery; Gelatin sponge; Hemostasis; Surgical sealant.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Gelatin Sponge, Absorbable*
  • Hemostasis
  • Hemostasis, Surgical / methods*
  • Hemostatics / therapeutic use*
  • Humans
  • In Vitro Techniques
  • Silicones / therapeutic use
  • Time Factors

Substances

  • Hemostatics
  • Silicones