Alterations in Doppler-derived renal venous stasis index during recompensation of right heart failure and fluid overload in a patient with pulmonary hypertension

Rev Cardiovasc Med. 2019 Dec 30;20(4):263-266. doi: 10.31083/j.rcm.2019.04.564.

Abstract

Renal congestion is becoming recognized as a potential contributor to cardiorenal syndromes. Adequate control of congestion with simultaneous preservation of renal function has been proposed as a central goal of the management of heart failure. We report our care of a 48-year-old woman suffering from right heart failure and massive fluid overload due to severe pulmonary hypertension secondary to a combination of left-heart disease and status after recurrent pulmonary embolisms. Alterations in Doppler-derived intrarenal venous flow patterns and a novel renal venous stasis index were used to evaluate improvement in renal venous congestion during recompensation. Due to refractory congestion despite optimal medical treatment and continuous veno-venous hemodialysis, a peritoneal dialysis catheter was placed to relieve the massive ascites. The paracentesis of ascites led to a significant loss of weight, normalization of hydration status with subsequent termination of continuous veno-venous hemodialysis, and a significant improvement in clinical and echocardiographic parameters. Renal Doppler ultrasonography showed continuous improvement in intrarenal venous flow patterns and the renal venous stasis index indicative of effective decongestion up to a normal intrarenal venous flow pattern and renal venous stasis index. Furthermore, residual renal function increased during follow-up. This case demonstrates the feasibility of renal Doppler ultrasonography as a simple, non-invasive, and integrative measure of renal congestion. The renal venous stasis index and intrarenal venous flow patterns may be useful to evaluate the treatment response and to guide therapy in patients with right heart failure.

Keywords: Cardiorenal syndromes; pulmonary hypertension; renal Doppler ultrasonography; venous congestion.

Publication types

  • Case Reports

MeSH terms

  • Blood Flow Velocity
  • Cardio-Renal Syndrome / diagnostic imaging
  • Cardio-Renal Syndrome / etiology
  • Cardio-Renal Syndrome / physiopathology
  • Cardio-Renal Syndrome / therapy*
  • Female
  • Heart Failure / diagnosis
  • Heart Failure / etiology
  • Heart Failure / physiopathology
  • Heart Failure / therapy*
  • Humans
  • Hypertension, Pulmonary / complications
  • Hypertension, Pulmonary / diagnostic imaging
  • Hypertension, Pulmonary / physiopathology
  • Hypertension, Pulmonary / therapy*
  • Middle Aged
  • Renal Circulation
  • Renal Veins / diagnostic imaging*
  • Renal Veins / physiopathology
  • Treatment Outcome
  • Ultrasonography, Doppler*
  • Ventricular Dysfunction, Right / diagnostic imaging
  • Ventricular Dysfunction, Right / etiology
  • Ventricular Dysfunction, Right / physiopathology
  • Ventricular Dysfunction, Right / therapy*
  • Ventricular Function, Right*
  • Water-Electrolyte Balance*
  • Water-Electrolyte Imbalance / diagnosis
  • Water-Electrolyte Imbalance / etiology
  • Water-Electrolyte Imbalance / physiopathology
  • Water-Electrolyte Imbalance / therapy*