Susac syndrome and pregnancy: a relationship to clarify. About two cases and review of the literature

J Matern Fetal Neonatal Med. 2022 Jan;35(1):181-186. doi: 10.1080/14767058.2020.1712712. Epub 2020 Jan 14.

Abstract

Background: Susac syndrome is a vasculopathy that affects the central nervous system, mainly the brain parenchyma, retina and inner ear. It affects mainly young women and. Management is based on expert consensus and in pregnant women the treatment is not well established. It is necessary to start treatment early because of its potential severity and sequelae.

Method: We present two cases of Susac syndrome related to pregnancy/puerperium and performed a review of the literature.

Conclusions: Susac syndrome is a disease that requires a high clinical suspicion, especially in pregnant women. Treatment in pregnancy or puerperium is not well established.

Précis: Susac syndrome is a disease that requires a high clinical suspicion, especially in pregnant women. Treatment in pregnancy or puerperium is not well established.

Keywords: Pregnancy; autoimmunity; cerebral vasculopathy; relapse; susac syndrome.

Publication types

  • Review

MeSH terms

  • Brain
  • Central Nervous System
  • Disease Progression
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Pregnancy
  • Retina
  • Susac Syndrome* / diagnosis