Effectiveness and safety of robotic versus traditional laparoscopic gastrectomy for gastric cancer: An updated systematic review and meta-analysis

J Cancer Res Ther. 2019;15(7):1450-1463. doi: 10.4103/jcrt.JCRT_798_18.

Abstract

Gastrectomy is considered the gold standard treatment for gastric cancer patients. Currently, there are two minimally invasive surgical methods to choose from, robotic gastrectomy (RG) and laparoscopic gastrectomy (LG). Nevertheless, it is still unclear which is superior between the two. This meta-analysis aimed to investigate the effectiveness and safety of RG and LG for gastric cancer. A systematic literature search was performed using PubMed, Embase, and the Cochrane Library databases until September 2018 in studies that compared RG and LG in gastric cancer patients. Operative and postoperative outcomes analyzed were assessed. The quality of the evidence was rated using the Grading of Recommendations, Assessment, Development and Evaluations. Twenty-four English studies were analyzed. The meta-analysis revealed that the RG group had a significantly longer operation time, lower intraoperative blood loss, and higher perioperative costs compared to the LG group. However, there were no differences in complications, conversion rate, reoperation rate, mortality, number of lymph nodes harvested, days of first flatus, postoperative hospitalization time, and survival rate between the two groups. RG was shown to be associated with decreased intraoperative blood loss and increased perioperative cost and operation time compared to LG. Several higher-quality original studies and prospective clinical trials are required to confirm the advantages of RG.

Keywords: Gastric cancer; laparoscopic gastrectomy; meta-analysis; robot gastrectomy.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Age Factors
  • Blood Loss, Surgical
  • Body Mass Index
  • Flatulence
  • Gastrectomy* / adverse effects
  • Gastrectomy* / methods
  • Health Care Costs
  • Humans
  • Laparoscopy* / adverse effects
  • Laparoscopy* / methods
  • Length of Stay
  • Operative Time
  • Postoperative Complications / etiology
  • Robotic Surgical Procedures* / adverse effects
  • Robotic Surgical Procedures* / methods
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / mortality
  • Stomach Neoplasms / surgery*
  • Treatment Outcome