Disruptor of telomeric silencing 1-like (DOT1L) is involved in breast cancer metastasis via transcriptional regulation of MALAT1 and ZEB2

J Genet Genomics. 2019 Dec 20;46(12):591-594. doi: 10.1016/j.jgg.2019.11.008. Epub 2019 Dec 17.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast Neoplasms / genetics
  • Breast Neoplasms / metabolism*
  • Chromatin Immunoprecipitation
  • Female
  • Histone-Lysine N-Methyltransferase / metabolism*
  • Histones / metabolism
  • Humans
  • MCF-7 Cells
  • Neoplasm Metastasis / genetics
  • Protein Binding
  • RNA, Long Noncoding / genetics
  • RNA, Long Noncoding / metabolism*
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Zinc Finger E-box Binding Homeobox 2 / genetics
  • Zinc Finger E-box Binding Homeobox 2 / metabolism*

Substances

  • Histones
  • MALAT1 long non-coding RNA, human
  • RNA, Long Noncoding
  • RNA, Messenger
  • ZEB2 protein, human
  • Zinc Finger E-box Binding Homeobox 2
  • DOT1L protein, human
  • Histone-Lysine N-Methyltransferase