[A case of chronic adult T-cell leukemia benefited by small doses of MEPP]

Gan To Kagaku Ryoho. 1988 Dec;15(12):3291-5.
[Article in Japanese]

Abstract

A 59-year-old man diagnosed as a chronic ATL with cutaneous invasion, was treated with small doses of CPM, ADM, VDS and PSL regimens according to CHOP. The treatment was successful and achieved PR at the first stage of the therapy, but it became refractory later. He was then treated with small MEPP (MXT, VP-16, CDDP and PSL) as the salvage therapy for non-Hodgkin's lymphoma. This case suggested that small MEPP might be a useful combination chemotherapy for ATL.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Chronic Disease
  • Cisplatin / administration & dosage
  • Drug Administration Schedule
  • Etoposide / administration & dosage
  • Humans
  • Leukemia, T-Cell / drug therapy*
  • Leukemia, T-Cell / pathology
  • Male
  • Middle Aged
  • Mitoxantrone / administration & dosage
  • Prednisolone / administration & dosage
  • Skin / pathology

Substances

  • Etoposide
  • Prednisolone
  • Mitoxantrone
  • Cisplatin

Supplementary concepts

  • MEPP protocol