Brazilian consensus on the diagnosis and treatment of extremities soft tissue sarcomas

J Surg Oncol. 2020 Apr;121(5):743-758. doi: 10.1002/jso.25847. Epub 2020 Jan 22.

Abstract

Introduction: Soft tissue sarcomas (STSs) are rare tumors and constitute only 1% of all tumors in adults. Indeed, due to their rarity, most cases in Brazil are not treated according to primary international guidelines.

Methods: This consensus addresses the treatment of STSs in the extremities. It was made by workgroups from Brazilian Societies of Surgical Oncology, Orthopaedics, Clinical Oncology, Pathology, Radiology and Diagnostic Imaging, and Radiation Oncology. The workgroups based their arguments on the best level of evidence in the literature and recommendations were made according to diagnosis, staging, and treatment of STSs. A meeting was held with all the invited experts and the topics were presented individually with the definition of the degree of recommendation, based on the levels of evidence in the literature.

Results: Risk factors and epidemiology were described as well as the pathological aspects and imaging. All recommendations are described with the degree of recommendation and levels of evidence.

Conclusion: Recommendations based on the best literature regional aspects were made to guide professionals who treat STS. Separate consensus on specific treatments for retroperitoneal, visceral, trunk, head and neck sarcomas, and gastrointestinal stromal tumor, are not contemplated into this consensus.

Keywords: multidisciplinary sarcoma; sarcoma consensus; sarcoma reference cancer centers; soft tissue sarcomas.

Publication types

  • Consensus Development Conference

MeSH terms

  • Biopsy
  • Brazil
  • Chemotherapy, Adjuvant
  • Extremities / pathology*
  • Extremities / surgery
  • Humans
  • Lymph Nodes / pathology
  • Neoplasm Metastasis / diagnosis
  • Neoplasm Metastasis / therapy
  • Neoplasm Staging
  • Palliative Care
  • Postoperative Complications / therapy
  • Radiotherapy, Adjuvant
  • Risk Factors
  • Sarcoma / diagnostic imaging
  • Sarcoma / pathology
  • Sarcoma / therapy*
  • Soft Tissue Neoplasms / diagnostic imaging
  • Soft Tissue Neoplasms / pathology
  • Soft Tissue Neoplasms / therapy*