Cognitive testing of the PHQ-9 for depression screening among pregnant and postpartum women in Kenya

BMC Psychiatry. 2020 Jan 29;20(1):31. doi: 10.1186/s12888-020-2435-6.

Abstract

Background: African women face high rates of depression, particularly during pregnancy or postpartum or after a recent HIV diagnosis. The Patient Health Questionnaire-9 (PHQ-9) depression screening tool has been quantitatively validated and extensively used to identify depression and link individuals to care. However, qualitative work is necessary to identify important opportunities to improve PHQ-9 question comprehension and performance among Kenyan women.

Methods: We administered the Kiswahili or English PHQ-9 (based on preference) to 29 pregnant and postpartum women in Thika, Kenya. Following administration, we conducted cognitive interviews with a purposive sample of 20 women. We used analytic memos and data matrices to identify themes around scale acceptability, comprehension, and decision and response processes.

Results: Most participants preferred to answer the PHQ-9 in Kiswahili (N = 15; 52%). Among the 20 interview participants, 12 (60%) had scores ≥5, indicating depressive symptoms. Overall, participants found the scale acceptable as an interviewer-administered tool. Participants reported few problems related to comprehension but had difficulty answering items not relevant to their lives (e.g., "watching television") and double-barreled items (e.g., "poor appetite or overeating"). They were hesitant to endorse items related to "duties as a wife and mother" and suicidal ideation. Most participants had difficulty distinguishing between response options of "several days" and "more than half the days".

Conclusions: We detected several problems related to PHQ-9 comprehension, decision processes, and response processes. We provide recommended changes to instructions and item wording to improve PHQ-9 validity among Kenyan women.

Keywords: Depression; Kenya; PHQ-9; Pregnancy; Women.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Depression, Postpartum / diagnosis*
  • Depression, Postpartum / psychology
  • Female
  • HIV Infections / epidemiology
  • HIV Infections / psychology
  • Humans
  • Kenya / epidemiology
  • Mass Screening / methods
  • Mass Screening / standards*
  • Mental Status and Dementia Tests / standards*
  • Mothers / psychology
  • Patient Health Questionnaire / standards*
  • Pilot Projects
  • Postpartum Period / psychology
  • Pregnancy
  • Pregnancy Complications / diagnosis*
  • Pregnancy Complications / epidemiology
  • Pregnancy Complications / psychology
  • Reproducibility of Results
  • Suicidal Ideation
  • Young Adult