Failure of antiviral therapy with brincidofovir in non-HIV progressive multifocal leukoencephalopathy

Acta Neurol Belg. 2020 Oct;120(5):1225-1226. doi: 10.1007/s13760-020-01301-w. Epub 2020 Feb 18.

Authors

Jean-Philippe Talarmin¹, Schéhérazade Rezig², Adissa Tran-Minoui³, Christian Berthou⁴, Jean-Richard Eveillard⁴

Affiliations

¹ Department of Internal Medicine and Infectious Diseases, Centre Hospitalier de Cornouaille, Quimper, France. [email protected].
² Department of Infectious Diseases, Centre Hospitalier Universitaire, Brest, France.
³ Department of Virology, Centre Hospitalier Universitaire, Brest, France.
⁴ Department of Hematology, Centre Hospitalier Universitaire, Brest, France.

PMID: 32072465
DOI: 10.1007/s13760-020-01301-w

No abstract available

Keywords: Brincidofovir; CMX001; JC virus; Progressive multifocal leukoencephalopathy.

Publication types

Case Reports
Letter

MeSH terms

Antiviral Agents / therapeutic use*
Cytosine / analogs & derivatives*
Cytosine / therapeutic use
Fatal Outcome
Female
Humans
Leukoencephalopathy, Progressive Multifocal / drug therapy*
Male
Middle Aged
Organophosphonates / therapeutic use*
Treatment Failure*

Substances

Antiviral Agents
Organophosphonates
brincidofovir
Cytosine