Liver Retransplantation: The Changing Scenario in a Tertiary Medical Center

Transplant Proc. 2020 Mar;52(2):543-545. doi: 10.1016/j.transproceed.2019.12.026. Epub 2020 Feb 19.

Abstract

Aim: To analyze the causes of liver retransplantation (LRT), which mostly depend on recipient factors.

Materials and methods: A descriptive, observational, and unicentric study including patients who underwent an LRT in a tertiary medical center between April 2002 and December 2018. Recipient, donor, and liver transplant data were collected.

Results: During the period under review a total of 468 transplants were made; among them, 32 (6.8%) were LRT. The most common indication (25%) was hepatic artery thrombosis (HAT) developing ischemic cholangiopathy followed by chronic rejection (21.8%). Late LRT was performed in 71.8%. A total of 96.8% of donations were after brain death with a donor median age of 65 years. Six patients (18.7%) had HAT as a postoperative complication. The recipients' 3-, 6-, and 12-month overall survival was 72.7%, 54.6%, and 51.5%, respectively, and the 5-year was 46.8%. Leading cause of death was septic shock (42.1%).

Conclusion: In our patients, the most common cause of LRT is HAT. We had an LRT rate of 6.8%, which is consistent with national and international registers.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Female
  • Graft Survival
  • Hepatic Artery / surgery*
  • Humans
  • Liver Diseases / mortality
  • Liver Diseases / surgery
  • Liver Transplantation / methods
  • Liver Transplantation / mortality*
  • Male
  • Middle Aged
  • Postoperative Complications / etiology
  • Postoperative Complications / mortality
  • Postoperative Complications / surgery*
  • Reoperation / methods
  • Reoperation / mortality*
  • Survival Rate
  • Tertiary Care Centers
  • Thrombosis / etiology
  • Thrombosis / mortality
  • Thrombosis / surgery
  • Tissue Donors / statistics & numerical data*