Basophil activation test in cancer patient blood evaluating potential hypersensitivity to an anti-tumor IgE therapeutic candidate

Allergy. 2020 Aug;75(8):2069-2073. doi: 10.1111/all.14245. Epub 2020 Mar 10.

Heather J Bax^{1

2}, Atousa Khiabany^{1

2}, Chara Stavraka^{1

2

3}, Giulia Pellizzari¹, Charleen Chan Wah Hak^{1

3}, Alexandra Robinson¹, Kristina M Ilieva^{1

4}, Natalie Woodman⁵, Cristina Naceur-Lombardelli⁵, Cheryl Gillett⁵, Sarah Pinder⁵, Hannah J Gould^{6

7}, Christopher J Corrigan^{7

8}, Stephen J Till^{7

8}, Sidath Katugampola⁹, Claire Barton^{9

10}, Anna Winship³, Sharmistha Ghosh³, Ana Montes³, Debra H Josephs^{1

2

3}, James F Spicer^{2

3}, Sophia N Karagiannis^{1

4}

¹ St. John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London, London, UK.
² School of Cancer & Pharmaceutical Sciences, King's College London, Guy's Hospital, London, UK.
³ Departments of Medical Oncology and Clinical Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁴ Breast Cancer Now Research Unit, School of Cancer & Pharmaceutical Sciences, Guy's Cancer Centre, King's College London, London, UK.
⁵ King's Health Partners Cancer Biobank, School of Cancer & Pharmaceutical Sciences, King's College London, London, UK.
⁶ Randall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, King's College London, London, UK.
⁷ Asthma UK Centre, Allergic Mechanisms in Asthma, King's College London, London, UK.
⁸ Department of Respiratory Medicine and Allergy and School of Immunology and Microbial Sciences, King's College London, London, UK.
⁹ Centre for Drug Development, Cancer Research UK, London, UK.
¹⁰ Barton Oncology Ltd, Eastcote, UK.

No abstract available

Keywords: BAT; IgE; MOv18; basophils; ovarian cancer.

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