Danger in the jungle: sensible care to reduce avoidable acute kidney injury in hospitalized children

Samira Bell; Nicholas M Selby; Sean M Bagshaw

doi:10.1016/j.kint.2019.11.020

Danger in the jungle: sensible care to reduce avoidable acute kidney injury in hospitalized children

Kidney Int. 2020 Mar;97(3):458-460. doi: 10.1016/j.kint.2019.11.020.

Authors

Samira Bell¹, Nicholas M Selby², Sean M Bagshaw³

Affiliations

¹ Division of Population Health and Genomics, University of Dundee, Dundee, UK.
² Centre for Kidney Research and Innovation, Division of Medical Sciences and Graduate Entry Medicine, University of Nottingham, Nottingham, UK.
³ Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. Electronic address: [email protected].

PMID: 32087888
DOI: 10.1016/j.kint.2019.11.020

Abstract

When children require hospital admission, many receive medications with nephrotoxic potential. As such, this can translate into an increased risk of acute kidney injury. In this context, acute kidney injury is hospital acquired, often iatrogenic, and portends risk of adverse outcomes. The Nephrotoxic Injury Negated by Just-in-Time Action study implemented a multicenter hospital-wide quality improvement initiative to detect and reduce nephrotoxin exposure in children aimed at decreasing the rates of potentially avoidable acute kidney injury. This commentary explores the findings and implications of the Nephrotoxic Injury Negated by Just-in-Time Action study.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Acute Kidney Injury*
Child
Child, Hospitalized
Drug-Related Side Effects and Adverse Reactions*
Humans
Prospective Studies
Quality Improvement