Rituximab for maintenance of remission in ANCA-associated vasculitis: expert consensus guidelines

Joanna Tieu; Rona Smith; Neil Basu; Paul Brogan; David D'Cruz; Neeraj Dhaun; Oliver Flossmann; Lorraine Harper; Rachel B Jones; Peter C Lanyon; Raashid A Luqmani; Stephen P McAdoo; Chetan Mukhtyar; Fiona A Pearce; Charles D Pusey; Joanna C Robson; Alan D Salama; Lucy Smyth; Richard A Watts; Lisa C Willcocks; David R W Jayne

doi:10.1093/rheumatology/kez640

Rituximab for maintenance of remission in ANCA-associated vasculitis: expert consensus guidelines

Rheumatology (Oxford). 2020 Apr 1;59(4):e24-e32. doi: 10.1093/rheumatology/kez640.

Authors

Joanna Tieu^{1

2}, Rona Smith¹, Neil Basu³, Paul Brogan^{4

5}, David D'Cruz⁶, Neeraj Dhaun^{7

8}, Oliver Flossmann⁹, Lorraine Harper¹⁰, Rachel B Jones^{1

11}, Peter C Lanyon^{12

13}, Raashid A Luqmani¹⁴, Stephen P McAdoo¹⁵, Chetan Mukhtyar^{16

17}, Fiona A Pearce^{18

19}, Charles D Pusey¹⁵, Joanna C Robson^{20

21}, Alan D Salama^{22

23}, Lucy Smyth²⁴, Richard A Watts^{25

26}, Lisa C Willcocks¹¹, David R W Jayne^{1

27}

Affiliations

¹ Department of Medicine, University of Cambridge, Cambridge, UK.
² Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.
³ Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow.
⁴ University College London Great Ormond Institute of Child Health.
⁵ Great Ormond Street Hospital NHS Foundation Trust, London, UK.
⁶ Guy's and St Thomas' NHS Foundation Trust, London.
⁷ British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh.
⁸ Royal Infirmary of Edinburgh, Edinburgh.
⁹ Berkshire Kidney Unit, Royal Berkshire Hospital, Reading.
¹⁰ Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham.
¹¹ Department of Renal Medicine, Cambridge University Hospitals Trust, Cambridge.
¹² Department of Rheumatology, Nottingham University Hospitals NHS Trust.
¹³ Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham.
¹⁴ Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Science, University of Oxford, Oxford.
¹⁵ Department of Medicine, Imperial College London, London.
¹⁶ Norfolk and Norwich University Hospital.
¹⁷ University of East Anglia, Norwich.
¹⁸ University of Nottingham.
¹⁹ Nottingham University Hospitals NHS Trust, Nottingham.
²⁰ Faculty of Health and Applied Sciences, University of West of England.
²¹ Department of Rheumatology, University Hospitals Bristol NHS Trust, Bristol.
²² University College London.
²³ Department of Renal Medicine, Royal Free Hospital, London.
²⁴ Exeter Kidney Unit, Royal Devon and Exeter Hospital, Exeter.
²⁵ Ipswich Hospital, Ipswich.
²⁶ Norwich Medical School, University of East Anglia, Norwich, UK.
²⁷ Vasculitis and Lupus Unit, Cambridge University Hospitals NHS Trust, Cambridge, UK.

PMID: 32096545
DOI: 10.1093/rheumatology/kez640

No abstract available

Keywords: Pneumocystis jirovecii; ANCA-associated vasculitis; hypogammaglobulinaemia; practise guideline; rituximab.

Publication types

Consensus Development Conference
Research Support, Non-U.S. Gov't

MeSH terms

Agammaglobulinemia / chemically induced
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / drug therapy*
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / physiopathology
Antirheumatic Agents / therapeutic use*
Churg-Strauss Syndrome / drug therapy
Churg-Strauss Syndrome / physiopathology
Delphi Technique
Duration of Therapy
Granulomatosis with Polyangiitis / drug therapy
Granulomatosis with Polyangiitis / physiopathology
Humans
Immunocompromised Host
Influenza Vaccines / therapeutic use
Influenza, Human / immunology
Influenza, Human / prevention & control
Maintenance Chemotherapy
Microscopic Polyangiitis / drug therapy
Microscopic Polyangiitis / physiopathology
Neutropenia / chemically induced
Pneumococcal Infections / immunology
Pneumococcal Infections / prevention & control
Pneumococcal Vaccines / therapeutic use
Pneumonia, Pneumocystis / immunology
Pneumonia, Pneumocystis / prevention & control
Practice Guidelines as Topic
Recurrence
Rituximab / therapeutic use*
Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
United Kingdom

Substances

Antirheumatic Agents
Influenza Vaccines
Pneumococcal Vaccines
Rituximab
Trimethoprim, Sulfamethoxazole Drug Combination