The possible role of substances inhibiting protein synthesis on the treatment of the spongiform encephalopathies

K O Schwarz

doi:10.1016/0306-9877(88)90139-9

The possible role of substances inhibiting protein synthesis on the treatment of the spongiform encephalopathies

Med Hypotheses. 1988 Nov;27(3):189-91. doi: 10.1016/0306-9877(88)90139-9.

Author

K O Schwarz¹

Affiliation

¹ Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153.

PMID: 3211014
DOI: 10.1016/0306-9877(88)90139-9

Abstract

The transmissible spongiform encephalopathies are probably caused by infectious proteinaceous agents called prions. It is suggested that these encephalopathies may be amenable to treatment by substances which inhibit protein synthesis.

MeSH terms

Animals
Central Nervous System Diseases / drug therapy*
Drug Evaluation, Preclinical
Humans
Models, Biological*
Prions / drug effects
Protein Synthesis Inhibitors / therapeutic use*
Slow Virus Diseases / drug therapy*

Substances

Prions
Protein Synthesis Inhibitors