RETRACTED: Methyltransferase-like 1 (METTL1) served as a tumor suppressor in colon cancer by activating 7-methyguanosine (m7G) regulated let-7e miRNA/HMGA2 axis

Life Sci. 2020 May 15:249:117480. doi: 10.1016/j.lfs.2020.117480. Epub 2020 Mar 2.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. Concern was raised by a reader that the pictures of different cell lines in Fig. 3A and Fig. 4D were from the same cell line, suggesting repeated use of the same picture. The editor contacted the corresponding author for explanation, but there was no reply. Apologies are offered to readers of the journal that this was not detected during the submission process.

Keywords: 7-methyguanosine; Colon cancer; HMGA2; Let-7e miRNA; Methyltransferase-like 1.

Publication types

  • Retracted Publication

MeSH terms

  • Aged
  • Cell Line, Tumor
  • Colonic Neoplasms / genetics*
  • Female
  • Genes, Tumor Suppressor*
  • Guanosine / analogs & derivatives*
  • Guanosine / genetics
  • HMGA2 Protein / genetics*
  • Humans
  • Male
  • Methyltransferases / physiology*
  • MicroRNAs / genetics*
  • Middle Aged
  • Real-Time Polymerase Chain Reaction

Substances

  • HMGA2 Protein
  • HMGA2 protein, human
  • MicroRNAs
  • Guanosine
  • 7-methylguanosine
  • METTL1 protein, human
  • Methyltransferases