Stereotactic Radiofrequency Ablation of an Unresectable Intrahepatic Cholangiocarcinoma (ICC): Transforming an Aggressive Disease into a Chronic Condition

Cardiovasc Intervent Radiol. 2020 May;43(5):791-796. doi: 10.1007/s00270-020-02443-3. Epub 2020 Mar 11.

Abstract

In 2010, we reported on a 72-year-old patient with a large, unresectable cholangiocarcinoma with intrahepatic metastases, which was treated by stereotactic radiofrequency ablation (SRFA) in three consecutive sessions. Within the last nine years, the same patient has received seven additional ablation sessions for a total of ten recurrent intrahepatic lesions. One year after the last SRFA, the patient's liver function is still within the physiological range, suggesting that this approach is not only sufficient for locally controlling tumor disease, but also for sparing healthy tissue. Moreover, periods of hospitalization were relatively short, while procedure-related pain was generally mild. In summary, SRFA has turned an aggressive disease with a devastating prognosis into a chronic condition while improving the patient's quality of life.

Keywords: Cholangiocarcinoma; Inferior vena cava syndrome; Liver; Navigation; Stereotactic radiofrequency ablation; Stereotactic irreversible electroporation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bile Duct Neoplasms / diagnostic imaging
  • Bile Duct Neoplasms / pathology
  • Bile Duct Neoplasms / surgery*
  • Bile Ducts, Intrahepatic / diagnostic imaging
  • Bile Ducts, Intrahepatic / pathology
  • Bile Ducts, Intrahepatic / surgery*
  • Catheter Ablation / methods*
  • Cholangiocarcinoma / diagnostic imaging
  • Cholangiocarcinoma / pathology
  • Cholangiocarcinoma / surgery*
  • Chronic Disease
  • Humans
  • Male
  • Quality of Life
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome