PRKN-related familial Parkinson's disease: First molecular confirmation from East Africa

M C J Dekker; J M Suleiman; D Bhwana; W P Howlett; S M Rashid; R van Minkelen; B C Hamel

doi:10.1016/j.parkreldis.2020.02.014

PRKN-related familial Parkinson's disease: First molecular confirmation from East Africa

Parkinsonism Relat Disord. 2020 Apr:73:14-15. doi: 10.1016/j.parkreldis.2020.02.014. Epub 2020 Feb 29.

Authors

M C J Dekker¹, J M Suleiman², D Bhwana², W P Howlett², S M Rashid³, R van Minkelen⁴, B C Hamel⁵

Affiliations

¹ Department of Internal Medicine, Kilimanjaro Christian Medical Centre, P.O. Box 3010, Moshi Town, Kilimanjaro Region, Tanzania. Electronic address: [email protected].
² Department of Internal Medicine, Kilimanjaro Christian Medical Centre, P.O. Box 3010, Moshi Town, Kilimanjaro Region, Tanzania.
³ Department of General Surgery, Kilimanjaro Christian Medical Centre, P.O. Box 3010, Moshi Town, Kilimanjaro Region, Tanzania.
⁴ Department of Clinical Genetics, Erasmus MC, P.O. Box 2040, 3000, CA, Rotterdam, the Netherlands.
⁵ Department of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525, GA, Nijmegen, the Netherlands.

PMID: 32193156
DOI: 10.1016/j.parkreldis.2020.02.014

No abstract available

Keywords: East Africa; Genetics; Kilimanjaro; PARK2; PRKN gene’; PRKN-Related parkinsonism; Parkin; Parkinson's disease; Sub Sahara Africa; Tanzania.

Publication types

Case Reports
Letter

MeSH terms

Adult
Africa South of the Sahara
Africa, Eastern
Female
Humans
Middle Aged
Parkinson Disease / genetics*
Pedigree
Tanzania
Ubiquitin-Protein Ligases / genetics*

Substances

Ubiquitin-Protein Ligases
parkin protein