Adding Alirocumab to Rosuvastatin Helps Reduce the Vulnerability of Thin-Cap Fibroatheroma: An ALTAIR Trial Report

JACC Cardiovasc Imaging. 2020 Jun;13(6):1452-1454. doi: 10.1016/j.jcmg.2020.01.021. Epub 2020 Mar 18.
No abstract available

Publication types

  • Letter
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal, Humanized / administration & dosage*
  • Antibodies, Monoclonal, Humanized / adverse effects
  • Biomarkers / blood
  • Cholesterol, LDL / blood
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / therapy*
  • Drug Therapy, Combination
  • Dyslipidemias / blood
  • Dyslipidemias / diagnosis
  • Dyslipidemias / drug therapy*
  • Fibrosis
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage*
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects
  • PCSK9 Inhibitors
  • Percutaneous Coronary Intervention* / adverse effects
  • Percutaneous Coronary Intervention* / instrumentation
  • Plaque, Atherosclerotic*
  • Prospective Studies
  • Rosuvastatin Calcium / administration & dosage*
  • Rosuvastatin Calcium / adverse effects
  • Serine Proteinase Inhibitors / administration & dosage*
  • Serine Proteinase Inhibitors / adverse effects
  • Stents
  • Time Factors
  • Tomography, Optical Coherence
  • Treatment Outcome

Substances

  • Antibodies, Monoclonal, Humanized
  • Biomarkers
  • Cholesterol, LDL
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • PCSK9 Inhibitors
  • Serine Proteinase Inhibitors
  • Rosuvastatin Calcium
  • PCSK9 protein, human
  • alirocumab