Elevated glycine detected on in vivo magnetic resonance spectroscopy in a breast cancer patient: case report and literature review

BJR Case Rep. 2020 Feb 12;6(1):20190090. doi: 10.1259/bjrcr.20190090. eCollection 2020 Mar.

Abstract

Magnetic resonance spectroscopy (MRS) is a promising non-invasive diagnostic method that can detect and quantify endogenous tissue metabolites. High glycine levels obtained from ex vivo breast MRS have been associated with poor prognosis; however, glycine evaluation has not been reported regarding in vivo MRS. We report our finding in a breast cancer patient in whom pre-treatment but not post-treatment in vivo MRS showed elevated glycine and discuss the implications of this finding.

Publication types

  • Case Reports