Cranial ultrasound findings in preterm germinal matrix haemorrhage, sequelae and outcome

Pediatr Res. 2020 Mar;87(Suppl 1):13-24. doi: 10.1038/s41390-020-0780-2.

Abstract

Germinal matrix-intraventricular haemorrhage (GMH-IVH), periventricular haemorrhagic infarction (PHI) and its complication, post-haemorrhagic ventricular dilatation (PHVD), are still common neonatal morbidities in preterm infants that are highly associated with adverse neurodevelopmental outcome. Typical cranial ultrasound (CUS) findings of GMH-IVH, PHI and PHVD, their anatomical substrates and underlying mechanisms are discussed in this paper. Furthermore, we propose a detailed descriptive classification of GMH-IVH and PHI that may improve quality of CUS reporting and prediction of outcome in infants suffering from GMH-IVH/PHI.

Publication types

  • Review

MeSH terms

  • Brain / diagnostic imaging*
  • Cerebral Hemorrhage / complications
  • Cerebral Ventricles / diagnostic imaging*
  • Dilatation / methods
  • Echoencephalography / methods*
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Infant, Newborn, Diseases
  • Infant, Premature
  • Infant, Premature, Diseases / diagnostic imaging*
  • Magnetic Resonance Imaging
  • Neonatology
  • Treatment Outcome
  • Ultrasonography, Doppler / methods