All that glitters is not prostate cancer: incidental finding of PSMA-avid meningioma

Hell J Nucl Med. 2020 Jan-Apr;23(1):79-80. doi: 10.1967/s002449912007. Epub 2020 Mar 31.

Abstract

We present a case of a 79 year old patient with a medical history of unilateral nerve-sparing radical prostatectomy due to a pT3aN0 (Gleason score 7) prostate carcinoma. Because of slightly elevated prostate specific antigen (PSA) level (0.35ng/dL), a fluorine-18-prostate specific membrane antigen (18F-PSMA)-1007 positron emission tomography/computed tomography (PET/CT) scan was performed, showing no signs of malignant recurrence. However, a moderately PSMA-avid nodular lesion was observed in the left occipital region with homogeneous contrast enhancement, suggestive for a meningioma, which was confirmed on magnetic resonance imaging (MRI). One year later, the lesion was resected due to a small but significant growth. Histology confirmed the diagnosis of a transitional type meningioma (WHO grade 1).

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antigens, Surface / metabolism*
  • Glutamate Carboxypeptidase II / metabolism*
  • Humans
  • Incidental Findings*
  • Male
  • Meningeal Neoplasms / diagnostic imaging*
  • Meningeal Neoplasms / metabolism*
  • Meningioma / diagnostic imaging*
  • Meningioma / metabolism*
  • Positron Emission Tomography Computed Tomography*

Substances

  • Antigens, Surface
  • FOLH1 protein, human
  • Glutamate Carboxypeptidase II