Metastatic melanoma presenting as intravenous tumour thrombus

Jennifer Nguyen; Warren Clements; Catriona McLean; Andrew Haydon; Maggie Moore; Kenneth Sk Yap; Victoria Mar; Mark Shackleton

doi:10.1111/1754-9485.13019

Metastatic melanoma presenting as intravenous tumour thrombus

J Med Imaging Radiat Oncol. 2020 Dec;64(6):814-816. doi: 10.1111/1754-9485.13019. Epub 2020 Mar 30.

Authors

Jennifer Nguyen¹, Warren Clements^{2

3}, Catriona McLean⁴, Andrew Haydon^{5

6}, Maggie Moore⁵, Kenneth Sk Yap⁷, Victoria Mar¹, Mark Shackleton^{5

6}

Affiliations

¹ Victorian Melanoma Service, Alfred Health, Melbourne, Victoria, Australia.
² Department of Diagnostic Imaging, Alfred Health, Melbourne, Victoria, Australia.
³ Department of Surgery, Monash University, Melbourne, Victoria, Australia.
⁴ Department of Anatomical Pathology, Alfred Health, Melbourne, Victoria, Australia.
⁵ Department of Medical Oncology, Alfred Health, Melbourne, Victoria, Australia.
⁶ Department of Medicine, Monash University, Melbourne, Victoria, Australia.
⁷ Department of Nuclear Medicine and PET, Alfred Health, Melbourne, Victoria, Australia.

PMID: 32227569
DOI: 10.1111/1754-9485.13019

Abstract

Tumour thrombus is a complication that occurs when a malignancy invades into the vasculature, occluding its lumen. Here, we present a rare case of melanoma tumour thrombus of the great saphenous vein of the left thigh, which was diagnosed on ¹⁸ F-fluorodeoxyglucose positron emission tomography/computed tomography and ultrasound-guided biopsy, and responded well to immunotherapy with pembrolizumab.

Keywords: F-18 FDG PET/CT; immunotherapy; melanoma; metastasis; tumour thrombus.

Publication types

Case Reports

MeSH terms

Fluorodeoxyglucose F18
Humans
Melanoma* / diagnostic imaging
Melanoma* / drug therapy
Neoplasms, Second Primary*
Positron Emission Tomography Computed Tomography
Positron-Emission Tomography
Radiopharmaceuticals
Thrombosis*

Substances

Radiopharmaceuticals
Fluorodeoxyglucose F18