The complete genome sequence of Mycobacterium bovis Mb3601, a SB0120 spoligotype strain representative of a new clonal group

Infect Genet Evol. 2020 Aug:82:104309. doi: 10.1016/j.meegid.2020.104309. Epub 2020 Mar 30.

Abstract

Mycobacterium bovis strain Mb3601 was isolated from the lymph node of an infected bovine in a bovine tuberculosis highly enzoonotic area of Burgundy, France. It was selected to obtain a complete genome for a new clonal complex, mainly constituted by SB0120-spoligotype strains that we propose to name "European 3". It was recently described as "clonal group I" based on whole-genome SNP analysis of 87 French strains. Here we describe the 4,365,068 bp complete genome obtained by the combination of PacBio and Illumina technologies. This genome of 65.64% G + C content includes 4024 predicted protein-coding genes, 52 tRNA, 3 rRNA and 11 copies of IS6110.

Keywords: Complete genome; European 3 clonal complex; France; Mycobacterium bovis; SB0120.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cattle
  • France
  • Genome, Bacterial*
  • Mycobacterium bovis / genetics*
  • Tuberculosis, Bovine / microbiology
  • Whole Genome Sequencing