Thixotropic behavior of a microcrystalline cellulose-sodium carboxymethylcellulose gel

J Pharm Sci. 1988 Sep;77(9):799-801. doi: 10.1002/jps.2600770917.

Abstract

An extensive study has been made of the thixotropic behavior of a microcrystalline cellulose-sodium carboxymethylcellulose gel (2% weight) and of its modification due to physical factors such as agitation time, duration of storage at rest, and temperature. An empirical function, giving thixotropic area variation rate as a function of agitation time, was obtained and found to be practically independent of storage time.

MeSH terms

  • Carboxymethylcellulose Sodium / analysis*
  • Cellulose / analysis*
  • Chemical Phenomena
  • Chemistry, Physical
  • Gels
  • Methylcellulose / analogs & derivatives*
  • Rheology
  • Temperature
  • Time Factors

Substances

  • Gels
  • Cellulose
  • Methylcellulose
  • Carboxymethylcellulose Sodium