Including DPYD on Cancer Genetic Panels to Prevent Fatal Fluoropyrimidine Toxicity

J Natl Compr Canc Netw. 2020 Apr;18(4):372-374. doi: 10.6004/jnccn.2019.7527.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biomarkers*
  • Drug-Related Side Effects and Adverse Reactions / etiology*
  • Drug-Related Side Effects and Adverse Reactions / prevention & control*
  • Genetic Testing
  • Humans
  • Mutation
  • Neoplasms / complications*
  • Neoplasms / drug therapy
  • Neoplasms / genetics*
  • Pharmacogenomic Variants*
  • Polymorphism, Single Nucleotide
  • Prognosis
  • Pyrimidines / adverse effects*
  • Pyrimidines / therapeutic use
  • Treatment Outcome

Substances

  • Biomarkers
  • Pyrimidines
  • pyrimidine