Tocilizumab in patients with symptomatic Kaposi sarcoma herpesvirus-associated multicentric Castleman disease

Blood. 2020 Jun 18;135(25):2316-2319. doi: 10.1182/blood.2019004602.
No abstract available

MeSH terms

  • Adult
  • Anti-HIV Agents / therapeutic use
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Castleman Disease / drug therapy*
  • Castleman Disease / virology
  • Female
  • HIV Infections / complications
  • HIV Infections / drug therapy
  • Herpesviridae Infections / complications*
  • Herpesviridae Infections / drug therapy
  • Herpesvirus 8, Human / isolation & purification
  • Herpesvirus 8, Human / pathogenicity*
  • Humans
  • Interleukin-10 / blood
  • Interleukin-1beta / blood
  • Male
  • Middle Aged
  • Sarcoma, Kaposi / complications
  • Treatment Outcome
  • Valganciclovir / therapeutic use
  • Viral Load
  • Zidovudine / therapeutic use

Substances

  • Anti-HIV Agents
  • Antibodies, Monoclonal, Humanized
  • IL10 protein, human
  • Interleukin-1beta
  • Interleukin-10
  • Zidovudine
  • Valganciclovir
  • tocilizumab

Supplementary concepts

  • Multi-centric Castleman's Disease