Osteosarcoma and Epidermoid Cyst in the Cerebellopontine Angle of an Adult

World Neurosurg. 2020 Jul:139:223-225. doi: 10.1016/j.wneu.2020.04.017. Epub 2020 Apr 17.

Abstract

Background: Osteosarcoma is a common malignant bone tumor that occurs in children or adolescents but rarely in the skull. Epidermoid cysts, also known as cholesteatomas, represent approximately 0.2%-1.8% of all intracranial tumors. The occurrence of osteosarcoma with an epidermoid cyst is extremely rare.

Case description: A 41-year-old woman had both osteosarcoma and cholesteatoma in the left cerebellopontine angle. We resected the 2 tumors using the suboccipital retrosigmoid approach, and she received radiotherapy and chemotherapy after the surgery. One year after surgery, the patient is healthy and has recovered well.

Conclusions: Osteosarcomas and epidermoid cysts should be completely resected to prevent tumor recurrence and aseptic meningitis. Postoperative osteosarcoma treatment should include radiotherapy and chemotherapy to improve the survival rate of patients. It is hoped that this report will help clinicians in diagnosis and treatment of patients with similar conditions.

Keywords: Cerebellopontine angle; Epidermoid cyst; Osteosarcoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / complications
  • Brain Diseases / pathology*
  • Cerebellar Neoplasms / complications
  • Cerebellar Neoplasms / pathology*
  • Cerebellopontine Angle / pathology*
  • Cholesteatoma / complications
  • Cholesteatoma / pathology*
  • Epidermal Cyst / complications
  • Epidermal Cyst / pathology
  • Female
  • Humans
  • Osteosarcoma / complications
  • Osteosarcoma / pathology*