The evolution of computer science is fast. New softwares and devices are proposed to physicians. We have designed and developed a complete guiding system build up around one personal computer, to assist the anesthetist to deliver simultaneously many drugs to a patient. This system is constituted of three modules. The first module SPINA is used to select the most appropriate IV drug from a data base considering patient's age, weight, disease state and surgery. It helps to evaluate its pharmacokinetic. The second module CINA is used to prepare the infusion sheet. The third module, MINA is used, for the start up and control of drug delivery and to synchronize the infusion pumps. It is also possible to interact on the preprogrammed infusion sequences. To achieve a closed loop regulation we have developed a fourth module PC-SCOPE; it manages the data acquisition. Some guidelines of our further developments are also presented.