Marner's cataract (CAM) assigned to chromosome 16: linkage to haptoglobin

Clin Genet. 1988 Oct;34(4):272-5. doi: 10.1111/j.1399-0004.1988.tb02875.x.

Abstract

In the present study the kindred with Marner's cataract (CAM), which now comprises nine generations, was examined for linkage with 14 marker loci. We found strong evidence for linkage to haptoglobin, zmax = 8.33 at thetamax = 0.05 for males and thetamax = 0.04 for females.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cataract / genetics*
  • Chromosomes, Human, Pair 16*
  • Female
  • Genetic Linkage
  • Genetic Markers / analysis
  • Haptoglobins / genetics*
  • Humans
  • Male
  • Pedigree

Substances

  • Genetic Markers
  • Haptoglobins