Modulation of the intracellular inhibitory checkpoint SHP-1 enhances the antitumor activity of engineered NK cells

Cell Mol Immunol. 2021 May;18(5):1314-1316. doi: 10.1038/s41423-020-0443-6. Epub 2020 Apr 27.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Cell Engineering*
  • Cell Line
  • Humans
  • Intracellular Space / metabolism*
  • Killer Cells, Natural / metabolism*
  • Mice
  • Neoplasms / immunology*
  • Neoplasms / pathology
  • Protein Tyrosine Phosphatase, Non-Receptor Type 6 / metabolism*

Substances

  • Protein Tyrosine Phosphatase, Non-Receptor Type 6