Venetoclax and decitabine for relapsed paediatric myelodysplastic syndrome-related acute myeloid leukaemia with complex aberrant karyotype after second stem cell transplantation

Br J Haematol. 2020 Jun;189(6):e251-e254. doi: 10.1111/bjh.16682. Epub 2020 Apr 28.

Authors

Johannes Raedler¹, Sita Heyde¹, Marie Kolokythas¹, Anna Eichinger¹, Vera Binder¹, Irene Schmid¹, Christoph Klein¹, Tobias Feuchtinger¹, Michael H Albert¹

Affiliation

¹ Pediatric Hematology and Oncology, Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Germany.

PMID: 32342493
DOI: 10.1111/bjh.16682

No abstract available

Keywords: acute myeloid leukaemia; myelodysplastic syndrome; pediatric hematology; venetoclax.

Publication types

Case Reports
Letter

MeSH terms

Abnormal Karyotype*
Adolescent
Allografts
Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Bridged Bicyclo Compounds, Heterocyclic / administration & dosage
Decitabine / administration & dosage
Hematopoietic Stem Cell Transplantation*
Humans
Leukemia, Myeloid, Acute* / genetics
Leukemia, Myeloid, Acute* / therapy
Male
Myelodysplastic Syndromes* / genetics
Myelodysplastic Syndromes* / therapy
Recurrence
Sulfonamides / administration & dosage

Substances

Bridged Bicyclo Compounds, Heterocyclic
Sulfonamides
Decitabine
venetoclax