Colorectal Dysplasia and Cancer in Pediatric-Onset Ulcerative Colitis Associated With Primary Sclerosing Cholangitis

Clin Gastroenterol Hepatol. 2021 May;19(5):1067-1070.e2. doi: 10.1016/j.cgh.2020.04.055. Epub 2020 Apr 29.

Abstract

Inflammatory bowel disease (IBD), especially when associated with primary sclerosing cholangitis (PSC), is a risk factor for developing colorectal cancer (CRC).1-3 We aimed to determine the incidence of CRC in a large cohort of pediatric-onset PSC-ulcerative colitis (UC) patients.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Cholangitis, Sclerosing* / complications
  • Cholangitis, Sclerosing* / epidemiology
  • Colitis, Ulcerative* / complications
  • Colorectal Neoplasms* / epidemiology
  • Humans
  • Inflammatory Bowel Diseases* / complications
  • Risk Factors